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Psychedelic Information Theory

Shamanism in the Age of Reason

Search Results : hallucinogens

Showing 20 to 34 of 34

Psychedelic Neuroplasticity

... subject retains some of the visual effects of hallucinogens long after the drug should have metabolized;5 persisting reactions to neural stress imply neuroplasticity. Psychedelics have been used to facilitate cult induction and programming;6 indo...

Entoptic Hallucination

Entoptic hallucination, geometric hallucinations, or phosphenes, are one of the most commonly reported visual effects of psychedelics. Phosphenes are a sensation of light caused by excitation of the retina by mechanical or electrical means. Pressure ...

Effects of Chemical Stimulation of Electrically-Induced Phosphenes on their Bandwidth, Shape, Number and Intensity

The perception of patterns not resulting from viewing external objects but stimulated by cranial electrodes with pulse currents within the electroencephalographic frequency range ('phosphenes') has been investigated in earlier work. The experiments d...

How Hallucinogens Play Their Mind-Bending Games

... the researchers localized the effects of hallucinogens to the pyramidal neurons in layer V of the somatosensory cortex, a relatively high-level region known to modulate the activity of other sections in the cortex and subcortical areas. Usin...

Neuropharmacology of Hallucinogens : a brief introduction

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1-Aminomethylbenzocycloalkanes: conformationally-restricted hallucinogenic phen­ethylamine analogues as functionally-selective 5 HT2A receptor agonists

... of the more flexible phenethylamine type hallucinogens. In addition, (R)-2 is one of the most potent and selective compounds yet discovered in the in vivo drug discrimination assay. Further, 2 was found to be a functionally selective agonist...

Psychedelic Pharmacology

... and some promote neural activity. Like most hallucinogens, DMT is classified as a selective 5-HT2A partial or full agonist; also active at other 5-HT subtypes, at adrenal receptors, at Sigma-1 receptors, and at tertiary amine receptors. This me...

5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

... serotonin receptors respond to the action of hallucinogens and atypical antipsychotic drugs, we have examined the cellular and subcellular distribution of these receptors in the cerebral cortex of macaque monkeys (with a focus on prefrontal area...

From drugs to deprivation: a Bayesian framework for understanding models of psychosis

... of NMDA receptor antagonists, serotonergic hallucinogens, cannabinoids and dopamine agonists. Conclusion By acknowledging the importance of perception and perceptual aberration in mediating the positive symptoms of psychosis, the model als...

Behavioral tolerance to lysergic acid diethylamide is associated with reduced serotonin-2A receptor signaling in rat cortex.

... Tolerance to the behavioral effects of hallucinogens occurs in humans and animals. In this study, we used drug discrimination to establish a behavioral model of lysergic acid diethylamide (LSD) tolerance and examined whether tolerance to t...

What is Consciousness?

... dissociative, and psychedelic. All hallucinogens must first destabilize top-down coherence of consciousness to produce novel states of spontaneous organization between the modular sub-units; this is how all hallucination begins. Dissoc...

What Geometric Visual Hallucinations Tell Us about the Visual Cortex

... see geometric visual hallucinations after taking hallucinogens such as LSD, cannabis, mescaline or psilocybin; on viewing bright ickering lights; on waking up or falling asleep; in “near-death” experiences; and in many other syndromes. Kl ¨ u...

Ecstasy, Other Club Drugs, & Other Hallucinogens

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The Control Interrupt Model of Psychedelic Action

... it is possible to describe a model in which hallucinogens periodically interrupt the top-down modulatory control of perception to create sensory interference patterns, multisensory frame destabilization, and altered states of consciousness. B...

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