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Presynaptic uptake blockade hypothesis for LSD action at the lateral inhibitory synapse in Limulus

... (a) light-evoked and antidromically stimulated lateral inhibition is enhanced during superfusion of low (1-5 microM) concentrations of LSD and suppressed by higher (5-20 microM) concentrations; (b) these actions of LSD are markedly reduced by bath...

Local cortical lesions abolish lateral inhibition at direction selective cells in cat visual cortex

Many cells in the cat visual cortex display a strong selectivity for the direction of motion of an optimally oriented stimulus. Postsynaptic inhibition has been suggested to generate this direction selectivity in simple cells, but the intracortical p...

The Control Interrupt Model of Psychedelic Action

... discrimination in sensory detail; this is called lateral inhibition. Fast inhibition in the cortex can also be applied from the bottom-up as well as laterally, this is called the synaptic triad of fast inhibition. Inhibition can also be applied from...

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